Decarboxylative Arylation of Pyridine 1‐Oxides and Anilides with Benzoic Acid via Palladium‐Catalyzed C–H Functionalization

M. Dabiri*, S.I. Alavioon, S. K. Movahed (2019) European Journal of Organic Chemistry 2019, 1479-1487.

https://doi.org/10.1002/ejoc.201801373

Abstract

An efficient and straightforward protocol for the regioselective acyloxylation of N-arylarbamates via Pd-catalyzed C−H bond functionalization has been demonstrated. The aliphatic and benzoic acid derivatives were used as the acyloxyl source to convert aromatic sp² C−H bonds into C−O bonds. Additionally, the oxidative homocoupling of N-arylarbamates were evaluated and gave the corresponding homocoupled products in good yields.