Electrochemical Determination of Dextromethorphan on Reduced Graphene Oxide Modified Screen‐Printed Electrode after Electromembrane Extraction

A.R. Fakhari*, M.H. Koruni, H. Ahmar, A. Shahsavani, S.K. Movahed (2015) Electroanalysis 26 (3), 521–529.

https://doi.org/10.1002/elan.201300323

Abstract

In this paper, electromembrane extraction coupled with differential pulse voltammetry (DPV) on a reduced graphene oxide modified screen-printed carbon electrode (RGO-SPCE) for the determination of dextromethorphan (DXM) in urine and plasma has been described. DXM migrated from 4 mL of a donor phase across a thin layer of 2-nitrophenyl octyl ether (NPOE) immobilized in the pores of a porous hollow fiber, into a 20 µL acceptor phase (HCl) present inside the lumen of the fiber. Then, 15 µL of a 0.1 M NaOH solution was added to the acceptor phase and the mixture was analyzed using DPV.